| Catalog Number | GTX13157 |
| Product Name | 5-HT1F antibody |
| Product Description | Rabbit polyclonal to 5 - HT1F |
| Synonyms | 3355 | HTR1F | 182134 | P30939 | 5-HT1F | HTR1EL | MR77 | |
| Background | 5-HT1F is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. 5-HT1F is a member of the GPCR family (subfamily: Serotonin). Expression of 5-HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) |
| Tested Applications | IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
| Application Note | IHC-P: Use at a dilution of 1/100 - 1/200. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Target | 5-HT1F |
| Cellular Localization | Integral membrane protein |
| Purification | Immunogen affinity purified |
| Purification Note | The antibody is purified on a peptide immunogen affinity column |
| Storage Buffer | Preservative: 0.01% Sodium Azide; Constituents: PBS. pH 7.7 |
