| Catalog Number | GTX71371 |
| Product Name | 5-HT1F receptor antibody |
| Product Description | Rabbit Polyclonal to Human 5 - HT1F Receptor |
| Synonyms | 3355 | HTR1F | 182134 | P30939 | 5-HT1F | HTR1EL | MR77 | |
| Background | 5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5-HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Synthetic peptide - KLH conjugated |
| Tested Applications | IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
| Application Note | Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200. |
| Species Cross Reactivity | Human. Others not determined. |
| Target | 5-HT1F receptor |
| Cellular Localization | Integral membrane protein |
| Form Supplied | Liquid |
| Purification | Immunogen affinity purified. |
| Purification Note | Peptide immunogen affinity column |
| Storage Buffer | Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
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