| Catalog Number | GTX96225 |
| Product Name | ABCD1 antibody |
| Product Description | Mouse polyclonal to ABCD1 |
| Synonyms | ABC42, ALD, ALDP, AMN |
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. |
| Clonality | Polyclonal |
| Host | Mouse |
| Immunogen | ABCD1 (AAH15541, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. |
| Antigen Species | Human |
| Tested Applications | ELISA, Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | For ELISA (tested with immunogen): Use at an assay dependednt dilution. For WB: (tested against immunogen): Use at an assay dependednt dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. |
| Specificity | Not tested |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Recombinant protein |
| Target | ABCD1 |
| Form Supplied | Liquid |
| Purification | Unpurified |
| Purification Note | From polyclonal serum |
| Storage Buffer | Antiserum containing 50% glycerol |
| Storage Instruction | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Notes | Antibody reactive against recombinant protein with GST tag on ELISA. Please enquire about availability of recombinant protein. |
| Manufacturer & Mfg Part# | Abnova H00000215-A01Only available to US end-users. Not available outside of the US or for resale inside of the US. |
