| Catalog Number | GTX25362 |
| Product Name | ABCG8 antibody |
| Product Description | Rabbit polyclonal to ABCG8 |
| Background | ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile. |
| Clonality | polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | N-terminal synthetic peptide (Human). |
| Antigen Species | Human |
| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | WB: Use at a dilution of 1/500. Predicted molecular weight: 81 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Species Cross Reactivity | Cross-reacts with Human. Does not cross-react with Mouse. Not yet tested in other species. |
| Target | ABCG8 |
| Purification | Immunogen affinity purified |
| Storage Buffer | Preservative: NoneConstituents: PBS |
