Catalog Number | GTX25995 |
Product Name | VAM1 antibody |
Product Description | Goat polyclonal to VAM1 |
Synonyms | 51678 | MPP6 | 606959 | Q9NZW5 | PALS2 | VAM-1 | VAM1 | p55T | |
Background | Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like, ZO1-like, p55-like and LIN2-like, based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily. |
Clonality | Polyclonal |
Host | Goat |
Isotype | IgG |
Immunogen | Peptide with sequence QQVLENLTELPSS, from N Terminus of the protein sequence according to NP_057531 |
Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
Application Note | WB: Use at a concentration of 0.5 - 1.0 ¥ìg/ml. Detects a band of approximately 55-60 kDa (predicted molecular weight: 62 kDa). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
Species Cross Reactivity | Cross-reacts with Human. Expected to cross-react with Mouse (100% identity with immunogen) due to sequence homology. Not yet tested in other species. |
Positive Controls | HEK293 Lysate and Human Brain lysates |
Target | VAM1 |
Cellular Localization | Plasma membrane |
Purification | Immunogen affinity purified |
Purification Note | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Storage Buffer | Tris-saline pH 7.3 containing 0.5% BSA and 0.02% sodium azide |
Storage Instruction | Keep as concentrated solution. Store at 4¨¬C short term. For extended storage aliquot and store at -20¨¬C or below. Avoid freeze-thaw cycles. |
Notes | GenBank Accession Number ? NP_057531. |