| Catalog Number | GTX11527 |
| Product Name | ADAM8 antibody |
| Product Description | Rabbit polyclonal to ADAM8 |
| Synonyms | 101 | ADAM8 | 602267 | P78325 | CD156 | MS2 | |
| Background | Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant amino acid sequence homology to hemorrhagic snake venom proteins, including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Synthetic peptide (Human) corresponding to the amino terminal end of the catalytic domain. |
| Antigen Species | Human |
| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | WB: Use at a dilution of 1/1000. Detects bands of approximately 75 kDa and 60 kDa (in reduced sample). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Specificity | Does not react with other ADAMs. |
| Species Cross Reactivity | Cross-reacts with Human, Rat and Pig. Not yet tested in other species. |
| Target | ADAM8 |
| Cellular Localization | Cell Membrane |
| Purification | Immunogen affinity purified |
| Storage Buffer | Preservative: 0.05% Sodium Azide; Constituents: 50% Glycerol, PBS |
