| Catalog Number | GTX82850 |
| Product Name | ADAMTS5 antibody |
| Product Description | Rabbit Anti-ADAMTS5 Polyclonal Antibody |
| Synonyms | 11096 | ADAMTS5 | 605007 | Q9UNA0 | ADAMTS11 | ADMP-2 | |
| Background | ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Synthetic peptide: C I(442) L T S I D A S K P(451). GTX82850 immunogen corresponds to amino acid residues 442-451 of the human ADAMTS5 protein. |
| Antigen Species | Human |
| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | GTX82850 has been successfully used in Western blot procedures. In Western blot analysis of JJ012 cells this antibody detects a ~64 kDa protein representing ADAMTS5. Suggested dilution - 1:500. |
| Specificity | GTX82850 detects ADAMTS5 in human samples |
| Species Cross Reactivity | Human, others not tested. |
| Target | ADAMTS5 |
| Form Supplied | 100 ug of epitope affinity purified rabbit IgG (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide. |
| Storage Instruction | -20º C, Avoid Freeze/Thaw Cycles |
