| Catalog Number | GTX77964 |
| Product Name | Alpha 1c-Adrenoceptor (ADRA1A) Antibody |
| Product Description | Rabbit polyclonal to Alpha 1c-Adrenoceptor (ADRA1A) |
| Synonyms | GPCR Adrenergic |
| Background | The alpha 1c- Adrenergic Receptor, also known as alpha 1a-adrenoceptor, is activated by epinephrine and norepinephrine. This receptor mediates calcium release upon ligand binding. The alpha 1-c adrenoceptor is one of three subtypes of alpha 1-adrenergic receptor (alpha 1 c/a, alpha 1b, and alpha 1d). The alpha 1c receptor couples to phospholipase C via a GTP-binding protein insensitive to pertussis toxin. Three isoforms are generated by alternative splicing. However, the corresponding isoforms of the protein have similar ligand-binding properties, effector coupling, and tissue distribution. Expression of this receptor has been reported in prostate, liver, kidney, heart, brain, spinal cord, bladder, and various blood vessels. ESTs have been isolated from liver and testis libraries. Caution: The name ADRA1A has been used to describe both the alpha 1c adrenoceptor (human chromosome 20) and the alpha 1d adrenoceptor (human chromosome 8), and the alpha 1c adrenoceptor is also known as alpha 1a adrenoceptor. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Synthetic peptide - KLH conjugated. Peptide sequence identity/similarity to Mouse: 100/100%. Rat: 100/100%. |
| Antigen Species | Mouse |
| Tested Applications | Immunocytochemistry. The usefulness of this product in other applications has not been determined. |
| Species Cross Reactivity | Human. Others not determined. |
| Target | Alpha 1c-Adrenoceptor (ADRA1A) |
| Form Supplied | Liquid |
| Purification | Peptide immunogen affinity column |
| Storage Buffer | Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide |
| Storage Instruction | Long term: -70 °C; Short term: -4 °C |
