Catalog Number | GTX102069 |
Product Name | ADAMTSL-2 antibody |
Full Name | ADAMTS-like 2 |
Product Description | Rabbit polyclonal antibody to ADAMTSL2 (ADAMTS-like 2) |
Synonyms | FLJ45164 | KIAA0605 |
Background | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 796 and 938 of Human ADAMTSL2 |
Antigen Species | Human |
Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
Specificity | This antibody is specific to the Human ADAMTSL2 protein. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | 293T | H1299 | HepG2 |
Target | ADAMTSL2 |
Predicted Target Size(KDa) | 104.64 |
Cellular Localization | Secreted |
Form Supplied | Liquid |
Concentration | 1 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX102069 WB ImageSample(30 ¥ìg of whole cell lysate)A:H12997.5% SDS PAGEGTX102069 diluted at 1:500Print:Print