Catalog Number | GTX30795 |
Product Name | ZAP70 antibody |
Product Description | Rabbit polyclonal to ZAP70 |
Synonyms | 70 kDa zeta associated protein antibody EC 2.7.10.2 antibody FLJ17670 antibody FLJ17679 antibody Selective T cell defect antibody SRK antibody STD antibody Syk related tyrosine kinase antibody Truncated ZAP kinase antibody Tyrosine protein kinase ZAP70 antibody TZK antibody ZAP 70 antibody ZAP-70 antibody Zeta chain associated protein kinase 70kD antibody Zeta chain associated protein kinase 70kDa antibody Zeta chain associated protein kinase 70kDa isoform 1 antibody Zeta chain associated protein kinase 70kDa isoform 2 antibody Zeta chain TCR associated protein kinase 70kD antibody Zeta chain TCR associated protein kinase 70kDa antibody |
Background | ZAP70, a 70 kDa member of the Syk tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Mutations in ZAP70 gene results in a form of Severe Combined Immunodeficiency Syndrome (SCID) in humans. ZAP70 expression also defines a subset of Chronic Lymphocytic Leukemia (CLL) in patients with unmutated Ig gene and poor clinical course. |
Clonality | Polyclonal |
Host | Rabbit |
Isotype | IgG |
Immunogen | Human Zap70 protein |
Antigen Species | Human |
Tested Applications | Immunoprecipitation, Western blot. The usefulness of this product in other applications has not been determined. |
Application Note | For IP: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | Jurkat whole cell lysate |
Form Supplied | Liquid |
Purification | Affinity purified with antigen |
Storage Buffer | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide |
Storage Instruction | Keep as concentrated solution, aliquot and store at 4¡ÆC. Do not freeze. |