| Catalog Number | GTX70759 |
| Product Name | F2RL3 antibody |
| Product Description | Rabbit Polyclonal to Human Proteinase - Activated Receptor 4 |
| Synonyms | Par4 induced by effectors of apoptosis PAWR PRKC Apoptosis WT1 Regulator Prostate Apoptosis Response Protein 4 TRANSCRIPTIONAL REPRESSOR PAR4 WT1 Interacting Protein |
| Background | Proteinase-Activated Receptor 4 (PAR4) is a member of the Proteinase-Activated Receptor subfamily. Along with other protease-activated receptors, PAR4 mediates the effects of the enzyme, thrombin which include activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury. These cellular responses are triggered through proteolytic activation of the receptors by thrombin. It is believed that PAR3 functions as a cofactor for the cleavage and activation of PAR4. PAR4 expression has been documented in the periphery, primarily in blood platelets. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Synthetic peptide - KLH conjugated |
| Tested Applications | IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
| Application Note | For IHC-P: Use at an asssay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Target | F2RL3 |
| Form Supplied | Liquid |
| Purification | Immunogen affinity purified. |
| Purification Note | Peptide immunogen affinity column |
| Storage Buffer | Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
Image:img18049.jpgBone marrow Print:Print
