| Catalog Number | GTX23336 |
| Product Name | Rab3C antibody |
| Product Description | Rabbit polyclonal to Rab3C |
| Synonyms | 171058 | Rab3c | |
| Background | Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland, and pituitary. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Synthetic peptide: MASAQDARFGQKDSSDQN-C, corresponding to amino acids 9-26 of Rat Rab3C. |
| Antigen Species | Rat |
| Tested Applications | Immunoprecipitation, Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | Western Blot: use at a concentration of 2 μg/ml. Immunoprecipitation: Assay dependent. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a 22 kDa protein representing Rab 3C from AtT20 cell extract. |
| Species Cross Reactivity | Cross-reacts with Mouse. Not yet tested in other species. |
| Positive Controls | AtT20 cells |
| Target | Rab3C |
| Form Supplied | Liquid |
| Purification | Protein A purified |
| Storage Buffer | PBS, 1 mg/ml BSA, 0.05% sodium azide |
| Storage Instruction | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
Image:img4010.jpgRab 3c Western Rab3C antibody. Western blot of rab 3C on AtT20 cell lysate using GTX23336. Print:Print
