| Catalog Number | GTX25828 |
| Product Name | Y14 [4C4] antibody |
| Product Description | Mouse monoclonal [4C4] to Y14 |
| Synonyms | 9939 | RBM8A | 605313 | Q9Y5S9 | BOV-1A | BOV-1B | BOV-1C | MDS014 | RBM8 | RBM8B | Y14 | ZNRP | ZRNP1 | |
| Background | This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites. |
| Clonality | Monoclonal |
| Clone No | 4C4 |
| Host | Mouse |
| Isotype | IgG2b |
| Immunogen | Full length native protein (purified) (Human). |
| Antigen Species | Human |
| Tested Applications | ELISA, Immunocytochemistry, Immunoprecipitation, Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | ELISA: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 21 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Species Cross Reactivity | Cross-reacts with Human and Xenopus laevis. Not yet tested in other species. |
| Target | Y14 |
| Cellular Localization | Cytoplasmic and Nuclear |
| Form Supplied | Liquid |
| Concentration | 1.5 mg/ml |
| Purification | Protein A purified |
| Purification Note | Purified from tissue culture supernatant. |
| Storage Buffer | Preservative: 0.1% Sodium Azide; Constituents: PBS |
| Storage Instruction | Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C. Avoid freeze-thaw cycles. |
