Catalog Number | GTX15075 |
Product Name | Vancomycin [2F10] antibody |
Product Description | Mouse monoclonal [2F10] to Vancomycin |
Background | Until recently, Vancomycin was one of the most powerful antibiotics that no bacterial cell had resistance to. Vancomycin is a very successful glycopeptide antibiotic, attacking the D alanyl D alanine component of the cell wall. By binding to the D alanyl D alanine component, Vancomycin is able to interrupt the normal cell wall formation. However, recently cells have achieved resistance to vancomycin. The reason that the resistance is so effective is that these cells have modified the D alanyl D alanine components of the cell wall into D alanyl D lactate components. Although this may sound easy, the actual process involves a series of five or more genes. |
Clonality | Monoclonal |
Clone No | 2F10 |
Host | Mouse |
Isotype | IgM |
Immunogen | Vancomycin |
Tested Applications | ELISA, Immunofluorescence. The usefulness of this product in other applications has not been determined. |
Application Note | ELISA: Use at an assay dependent dilution. IF: Use at a dilution of 1/250 - 1/500. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
Specificity | This antibody shows 100% specificity for Vancomycin. |
Species Cross Reactivity | Not species specific. |
Target | Vancomycin |
Form Supplied | Liquid |
Purification | Purified IgM |
Purification Note | This antibody was purified by size exclusion chromatography. |
Storage Buffer | Preservative: 0.05% Sodium Azide; Constituents: 40% Glycerol, PBS. pH 7.2 |
Storage Instruction | Keep as concentrated solution. Store at 4¨¬C short term. For extended storage aliquot and store at -20¨¬C or below. Avoid freeze-thaw cycles. |