| Catalog Number | GTX108264 |
| Product Name | 15-Sep antibody |
| Product Description | Rabbit polyclonal antibody to 15-Sep (-) |
| Background | This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 102 and 165 of Human 15-Sep |
| Antigen Species | Human |
| Tested Applications | Dot Blot |
| Application Note | Further validation in progress. |
| Specificity | This antibody is specific to the peptide antigen from 15-Sep. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Synthetic peptide: 1:8,000 |
| Target | 15-Sep |
| Predicted Target Size(KDa) | 17.94 |
| Cellular Localization | Endoplasmic reticulum lumen |
| Form Supplied | Liquid |
| Concentration | 1 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
