| Catalog Number | GTX100009 |
| Product Name | 5HT1B Receptor antibody |
| Full Name | 5-hydroxytryptamine (serotonin) receptor 1B |
| Product Description | Rabbit polyclonal antibody to 5HT1B Receptor (5-hydroxytryptamine (serotonin) receptor 1B) |
| Synonyms | 5-HT1B | 5-HT1DB | HTR1D2 | HTR1DB | S12 |
| Background | The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 249 and 313 of Human 5HT1B Receptor |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human 5HT1B Receptor protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | HeLaS3 | HepG2 |
| Target | 5HT1B Receptor |
| Predicted Target Size(KDa) | 43.57 |
| Cellular Localization | Cell membrane |
| Form Supplied | Liquid |
| Concentration | 1 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX100009 WB ImageSample(30 μg of whole cell lysate)A:HeLa S3 (GTX14654)12% SDS PAGEGTX100009 diluted at 1:500Print:Print
