| Catalog Number | GTX101533 |
| Product Name | 7-Sep antibody |
| Full Name | septin 7 |
| Product Description | Rabbit polyclonal antibody to 7-Sep (septin 7) |
| Synonyms | CDC10 | CDC3 | Nbla02942 | SEPT7A |
| Background | This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. Although the exact function of this gene has not yet been determined, its high similarity to yeast CDC10 and the high conservative nature of eukaryotic cell cycle machinery suggest a similar role to that of its yeast counterpart. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 192 and 411 of Human 7-Sep |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human 7-Sep protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | 293T | A431 | H1299 | HeLaS3 | HepG2 | Molt-4 | Raji |
| Target | 7-Sep |
| Predicted Target Size(KDa) | 50.69 |
| Cellular Localization | Cytoplasm | Kinetochore | Spindle |
| Form Supplied | Liquid |
| Concentration | 1.02 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX101533 WB ImageSample(30 μg of whole cell lysate)A:HeLa S3(GTX14654)7.5% SDS PAGEGTX101533 diluted at 1:1000Print:Print
