Catalog Number | GTX100489 |
Product Name | ACADM antibody |
Full Name | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain |
Product Description | Rabbit polyclonal antibody to ACADM (acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain) |
Synonyms | ACAD1 | FLJ18227 | FLJ93013 | FLJ99884 | MCAD | MCADH |
Background | This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 243 and 409 of Human ACADM |
Antigen Species | Human |
Tested Applications | Dot Blot |
Application Note | Further validation in progress. |
Specificity | This antibody is specific to the Protein antigen from ACADM. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | Target recombinant protein |
Target | ACADM |
Predicted Target Size(KDa) | 46.6 |
Cellular Localization | Mitochondrion matrix |
Form Supplied | Liquid |
Concentration | 0.13 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |