| Catalog Number | GTX113654 |
| Product Name | AChR beta2 antibody |
| Full Name | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| Product Description | Rabbit polyclonal antibody to AChR beta2 (cholinergic receptor, nicotinic, beta 2 (neuronal)) |
| Synonyms | EFNL3 | nAChRB2 |
| Background | Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 25 and 243 of AChR beta2 |
| Antigen Species | Human |
| Tested Applications | Dot blot |
| Application Note | Further validation in progress. |
| Specificity | This antibody is specific to the Protein antigen from AChR beta2 . |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Target recombinant protein |
| Target | AChR beta2 |
| Predicted Target Size(KDa) | 57.03 |
| Cellular Localization | Cell junction | synapse | postsynaptic cell membrane | Cell membrane |
| Form Supplied | Liquid |
| Concentration | 0.65 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
