| Catalog Number | GTX114267 |
| Product Name | Acid Ceramidase antibody |
| Full Name | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| Product Description | Rabbit polyclonal antibody to Acid Ceramidase (N-acylsphingosine amidohydrolase (acid ceramidase) 1) |
| Synonyms | AC | ASAH | FLJ21558 | FLJ22079 | PHP | PHP32 |
| Background | This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 197 and 393 of Acid Ceramidase |
| Antigen Species | human |
| Tested Applications | Dot blot |
| Application Note | Further validation in progress |
| Specificity | This antibody is specific to the Protein antigen from Acid Ceramidase. |
| Species Cross Reactivity | human - Not yet tested in other species |
| Positive Controls | Target recombinant protein |
| Target | Acid Ceramidase |
| Predicted Target Size(KDa) | 44.65 |
| Cellular Localization | Lysosome |
| Form Supplied | Liquid |
| Concentration | 1.03 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
