| Catalog Number | GTX101921 |
| Product Name | ACVRL1 antibody |
| Full Name | activin A receptor type II-like 1 |
| Product Description | Rabbit polyclonal antibody to ACVRL1 (activin A receptor type II-like 1) |
| Synonyms | ACVRLK1 | ALK-1 | ALK1 | HHT | HHT2 | ORW2 | SKR3 | TSR-I |
| Background | This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 109 and 281 of Human ACVRL1 |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human ACVRL1 protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | H1299 | HepG2 |
| Target | ACVRL1 |
| Predicted Target Size(KDa) | 56.13 |
| Cellular Localization | Membrane |
| Form Supplied | Liquid |
| Concentration | 0.78 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX101921 WB ImageSample(30 μg of whole cell lysate)A:Hep G2(GTX27900)7.5% SDS PAGEGTX101921 diluted at 1:1000Print:Print
