| Catalog Number | GTX101385 |
| Product Name | adenosine kinase antibody |
| Full Name | adenosine kinase |
| Product Description | Rabbit polyclonal antibody to adenosine kinase (adenosine kinase) |
| Synonyms | AK |
| Background | This gene encodes adenosine kinase, an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 146 and 360 of adenosine kinase |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human adenosine kinase protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | A431 | HepG2 |
| Target | adenosine kinase |
| Predicted Target Size(KDa) | 40.55 |
| Form Supplied | Liquid |
| Concentration | 0.93 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX101385 WB ImageSample (30 ug of whole cell lysate) A: A431 (GTX27909) B: Hep G2 (GTX27900) 10% SDS PAGE adenosine kinase antibody GTX101385 diluted at 1:1000 Print:Print
