| Catalog Number | GTX106079 |
| Product Name | adenylate kinase 1 antibody |
| Full Name | adenylate kinase 1 |
| Product Description | Rabbit polyclonal antibody to adenylate kinase 1 (adenylate kinase 1) |
| Background | Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 158 of adenylate kinase 1 |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human adenylate kinase 1 protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | A549 | HCT116 |
| Target | adenylate kinase 1 |
| Predicted Target Size(KDa) | 21.64 |
| Cellular Localization | Cytoplasm |
| Form Supplied | Liquid |
| Concentration | 0.4 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX106079 WB ImageSample (30 ug of whole cell lysate) A: HCT11612% SDS PAGE GTX106079 diluted at 1:500 Print:Print
