Catalog Number | GTX105296 |
Product Name | ADH5 antibody |
Full Name | alcohol dehydrogenase 5 (class III), chi polypeptide |
Product Description | Rabbit polyclonal antibody to ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide) |
Synonyms | ADH-3 | ADHX | FDH | GSNOR |
Background | This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 277 of ADH5 |
Antigen Species | Human |
Tested Applications | Dot blot |
Application Note | Further validation in progress. |
Specificity | This antibody is specific to the Protein antigen from ADH5. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | Target recombinant protein |
Target | ADH5 |
Predicted Target Size(KDa) | 39.73 |
Cellular Localization | Cytoplasm |
Form Supplied | Liquid |
Concentration | 0.76 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |