| Catalog Number | GTX114241 |
| Product Name | ADH5 antibody |
| Full Name | alcohol dehydrogenase 5 (class III), chi polypeptide |
| Product Description | Rabbit polyclonal antibody to ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide) |
| Synonyms | ADH-3 | ADHX | FDH | GSNOR |
| Background | This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 184 and 366 of ADH5 |
| Antigen Species | human |
| Tested Applications | Dot blot |
| Application Note | Further validation in progress |
| Specificity | This antibody is specific to the Protein antigen from ADH5. |
| Species Cross Reactivity | human - Not yet tested in other species |
| Positive Controls | Target recombinant protein |
| Target | ADH5 |
| Predicted Target Size(KDa) | 39.73 |
| Cellular Localization | Cytoplasm |
| Form Supplied | Liquid |
| Concentration | 1.01 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
