Catalog Number | GTX98025 |
Product Name | DAP3 antibody |
Product Description | Mouse polyclonal to DAP3 |
Synonyms | DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29, bMRP-10 |
Background | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in the 5 UTR have been found for this gene; both variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. |
Clonality | Polyclonal |
Host | Mouse |
Immunogen | DAP3 (NP_004623, 237 a.a. ~ 344 a.a) partial recombinant protein with GST tag. |
Antigen Species | Human |
Tested Applications | ELISA, Western blot. The usefulness of this product in other applications has not been determined. |
Application Note | For ELISA (tested with immunogen): Use at an assay dependednt dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. |
Specificity | Not tested |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | Recombinant protein |
Target | DAP3 |
Form Supplied | Liquid |
Purification | Unpurified |
Purification Note | From polyclonal serum |
Storage Buffer | Antiserum containing 50% glycerol |
Storage Instruction | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid freeze-thaw cycles. |
Notes | Antibody reactive against recombinant protein with GST tag on ELISA. Please enquire about availability of recombinant protein. |
Manufacturer & Mfg Part# | Abnova H00007818-A01Only available to US end-users. Not available outside of the US or for resale inside of the US. |