| Catalog Number | GTX22556 |
| Product Name | DAP5 antibody |
| Product Description | Rabbit polyclonal to DAP5 |
| Synonyms | 1982 | EIF4G2 | 602325 | P78344 | AAG1 | DAP5 | NAT1 | p97 | |
| Background | Death Associated Protein 5 (DAP 5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP 5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP 5 is cleaved at Asp790. The C-terminal truncated form of DAP 5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Available on request. |
| Antigen Species | N/A |
| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | WB: Use at a concentration of 1 - 2 μg/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Specificity | This antibody recognizes the 97 kDa DAP 5. It does not cross-react with other DAP family members or with eIF4G. |
| Species Cross Reactivity | Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. |
| Target | DAP5 |
| Form Supplied | Liquid |
| Purification | Immunogen affinity purified |
| Storage Buffer | PBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
