| Catalog Number | GTX98901 |
| Product Name | QPRT antibody |
| Product Description | Mouse polyclonal to QPRT |
| Synonyms | QPRTase |
| Background | This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimers disease, and Huntingtons disease. |
| Clonality | Polyclonal |
| Host | Mouse |
| Immunogen | QPRT (NP_055113, 198 a.a. ~ 298 a.a) partial recombinant protein with GST tag. |
| Antigen Species | Human |
| Tested Applications | ELISA, Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | For WB: (tested against K-562 lysate): Use at an assay dependednt dilution. For ELISA (tested with immunogen): Use at an assay dependednt dilution. For WB: (tested against immunogen): Use at an assay dependednt dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. |
| Specificity | Not tested |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Recombinant protein |
| Target | QPRT |
| Form Supplied | Liquid |
| Purification | Unpurified |
| Purification Note | From polyclonal serum |
| Storage Buffer | Antiserum containing 50% glycerol |
| Storage Instruction | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid freeze-thaw cycles. |
| Notes | Antibody reactive against recombinant protein with GST tag on ELISA. Please enquire about availability of recombinant protein. |
| Manufacturer & Mfg Part# | Abnova H00023475-A01Only available to US end-users. Not available outside of the US or for resale inside of the US. |