Catalog Number | GTX113433 |
Product Name | FACA antibody |
Full Name | Fanconi anemia, complementation group A |
Product Description | Rabbit polyclonal antibody to FACA (Fanconi anemia, complementation group A) |
Synonyms | FA | FA-H | FA1 | FAA | FACA | FAH | FANCH | MGC75158 |
Background | The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 190 of FACA |
Antigen Species | human |
Tested Applications | WB,IHC-P,IF. The usefulness of this product in other applications has not been determined. |
Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000,IHC-P: 1:100-1:500,IF:1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
Specificity | This antibody is specific to the human FACA protein. |
Species Cross Reactivity | human - Not yet tested in other species |
Positive Controls | 293T | A431 | H1299 | HeLa |
Target | FACA |
Predicted Target Size(KDa) | 32.96 |
Cellular Localization | Nucleus | Cytoplasm |
Form Supplied | Liquid |
Concentration | 1 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX113433 WB ImageSample (30 ug of whole cell lysate) A: A431 (GTX27909) B: Hela 12% SDS PAGE GTX113433 diluted at 1:1000 GTX113433 IHC ImageImmunohistochemical analysis of paraffin-embedded OV90 xenograft, using FACA(GTX113433) antibody at 1:500 dilution.Print:Print