Catalog Number | GTX82326 |
Product Name | WD repeat protein 4 antibody |
Product Description | Chicken polyclonal to WD repeat protein 4 |
Background | Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3 UTR and thus encode the same protein products. |
Clonality | Polyclonal |
Host | Chicken |
Isotype | IgY |
Immunogen | Synthetic peptide - human WD repeat protein 4 |
Antigen Species | Human |
Tested Applications | Western Blot. The usefulness of this product in other applications has not been determined. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | See Application Note |
Target | WD repeat protein 4 |
Predicted Target Size(KDa) | 45.49kDa |
Form Supplied | Liquid |
Concentration | 1 mg/ml |
Purification | Affinity purified with antigen |
Purification Note | From polyclonal serum |
Storage Buffer | Phosphate-Buffered Saline containing no preservatives |
Storage Instruction | Keep as concentrated solution. Store at 4¡ÆC short term. For extended storage aliquot and store at -20¡ÆC or below. Avoid freeze-thaw cycles. |