Catalog Number | GTX101212 |
Product Name | G6PD antibody |
Full Name | glucose-6-phosphate dehydrogenase |
Product Description | Rabbit polyclonal antibody to G6PD (glucose-6-phosphate dehydrogenase) |
Synonyms | G6PD1 |
Background | This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 219 of G6PD |
Antigen Species | human |
Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
Specificity | This antibody is specific to the human G6PD protein. |
Species Cross Reactivity | human - Not yet tested in other species |
Positive Controls | 293T | A431 | H1299 | HeLaS3 | HepG2 | Raji |
Target | G6PD |
Predicted Target Size(KDa) | 62.48 |
Form Supplied | Liquid |
Concentration | 6.37 mg/ml |
Purification | Affinity purified by Protein A. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX101212 WB ImageSample (30 ug of whole cell lysate)A: Hep G2 (GTX27900)7.5% SDS PAGEGTX101212 diluted at 1:1000Print:Print