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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-345255 |
AM06041PU-N |
38 Kda Mov34 Isologue (COPS5)//Human, Mouse/Mouse |
1/EA |
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문의 |
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Subject
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38 Kda Mov34 Isologue (COPS5) |
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Description
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/ Human, Mouse/Mouse |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Paraffin Sections, Western blot / Immunoblot, Immunoprecipitation |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 50 ug | | Reactivity | Human, Mouse | | Presentation | Purified | | Applications | Paraffin Sections, Western blot / Immunoblot, Immunoprecipitation | | Isotype | IgG2a | | Host | Mouse | | Clone | 6C3.38 | | PDF datasheet | view | | Shipping to | Not USA/Canada | | Synonyms | COPS5, CSN5, EC 3.4.-.-, JAB1, MGC3149, MOV-34, SGN5 | | Swiss Prot Num | Q92905 | | Immunogen | Recombinant full-length mouse JAB-1 gene expressed in E. coli | | Product Type | Antibodies | | Recommended Isotype Control | AM03096PU-N | | Storage | Store the antibody (in aliquots) at -20 °C to -70 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | |
| Format | State: Liquid Ig fraction | | ? | Purification: Protein G chromatography | | ? | Buffer System: Phosphate buffered saline | |
| Specificity | This antibody detects 38 Kda Mov34 Isologue (COPS5). | | Application | Immunoprecipitation. Western blot. Immunohistochemistry on paraffin sections (5 ?g/ml). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. | | Background | JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "Signalosome", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome. | |
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