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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-345256 |
AP05082PU-N |
3BP2//Mouse/Sheep |
1/EA |
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문의 |
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Subject
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3BP2 |
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Description
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/ Mouse/Sheep |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 250 ug | | Reactivity | Mouse | | Presentation | Purified | | Applications | Western blot / Immunoblot | | Isotype | IgG | | Host | Sheep | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | SH3 domain-binding protein 2 | | Immunogen | Antibody developed using SH2 domain of the 3BP2 protein fused to GST. | | Product Type | Antibodies | | Storage | The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Decker, M., et al. Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation. Immunity 1998, 9, 595 - 605 2. Songyang, Z., et al. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk and Vav. Mol. Cell Biol. 1994, 14, 2777 - 2785 | |
| Format | State: Liquid purified Ig | | ? | Purity: Purified | | ? | Buffer System: Phosphate buffered saline and 0.08% sodium azide | |
| Specificity | This antibody reacts to 3BP2. | | Application | Western Blot: Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. | | Background | 3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLCg 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66% homologous to the human protein at the amino acid level. | | Concentration | 1,0 mg/ml | |
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