| Synonyms | 5-Hydroxytryptamine Receptor 1F, Serotonin Receptor 1F, 5-HT-1F, HTR1EL, FocusOn042 |
| Swiss Prot Num | P30939 |
| Immunogen | Synthetic peptide - KLH conjugated, 3rd cytoplasmic domain of human |
| Product Type | Antibodies |
|
| Immunogen | Swiss Prot Num: P30939 |
| ? | Remarks: Mouse Identity: 75 % Mouse Similarity: 81 % Rat Identity: 81 % Rat Similarity: 88 % |
| Storage | Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
|
| Format | State: Liquid Ig fraction |
| ? | Purification: Immunoaffinity chromatography |
| ? | Buffer System: Phosphate buffered saline containing 0.09% sodium azide |
|
| Specificity | This antibody detects 5-HT1F Receptor (HTR1F) at 3rd cytoplasmic domain. |
| Application | Immunohistochemistry (6.5 ?g/ml). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Background | 5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. |
| Concentration | 1.0 mg/ml |
| Focuson | 042 Antibodies to 5-hydroxytryptamine (Serotonin) Receptors |
