| Synonyms | 5-hydroxytryptamine Receptor 7, Serotonin Receptor 7, 5-HT-7, 5HT7, 5-HT-X, FocusOn042 |
| Swiss Prot Num | P34969 |
| Immunogen | Synthetic peptide - KLH conjugated, 3rd cytoplasmic domain of human |
| Product Type | Antibodies |
|
| Immunogen | Swiss Prot Num: P34969 |
| ? | Remarks: Mouse Identity: 26 % Mouse Similarity: 26 % |
| Storage | Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
|
| Format | State: Liquid Ig fraction |
| ? | Purification: Immunoaffinity Chromatography |
| ? | Buffer System: Phosphate buffered saline containing 0.09% sodium azide |
|
| Specificity | This antibody detects 5-HT7 Receptor (HTR7) at 3rd cytoplasmic domain. |
| Application | Immunohistochemistry on paraffin sections (10 ?g/ml). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Background | 5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autistism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa. |
| Concentration | 1.0 mg/ml |
| Focuson | 042 Antibodies to 5-hydroxytryptamine (Serotonin) Receptors |
