| Synonyms | KAT2, Kynurenine aminotransferase II, Kynurenine-oxoglutarate aminotransferase II, Kynurenine-oxoglutarate transaminase II, 2-aminoadipate transaminase, 2-aminoadipate aminotransferase, Alpha-aminoadipate aminotransferase |
| Swiss Prot Num | Q8N5Z0 |
| Immunogen | Synthetic peptide - KLH conjugated, internal domain of human |
| Product Type | Antibodies |
| Storage | Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
|
| Format | State: Liquid Ig fraction |
| ? | Purification: Immunoaffinity chromatography |
| ? | Buffer System: Phosphate buffered saline, 0.09% sodium azide |
|
| Specificity | This antibody detects Aminoadipate Aminotransferase (AADAT) at internal domain. |
| Application | Immunohistochemistry on paraffin sections (5 ?g/ml). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Background | Kynurenine aminotransferase catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid. Kynurenic acid is an antagonist at the glycine site of NMDA receptors and increased levels of kynurenic acid are thought to exert a neuroprotective action in some pathological conditions. |
| Concentration | 1.0 mg/ml |
