Synonyms | DSRAD, G1P1, IFI4, P136, K88DSRBP |
Swiss Prot Num | P55266 |
Immunogen | GST fusion protein containing amino acid 1116-1176 of the rat DRADA coding sequence. The fusion protein was constructed in the pGEX-KG vector by inserting a fragment corresponding to nucleotides +3346 through +3525 of DRADA at the XbaI and XhoI sites in the vector. |
Product Type | Antibodies |
Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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Format | State: Liquid purified Ig (0.2um sterile filtered) |
? | Purity: Purified |
? | Buffer System: Phosphate buffered saline with 0.08% sodium azide |
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Specificity | This antibody reacts to DRADA. |
Application | Western Blot: 1:1000. |
Background | Double stranded RNA specific adenosine deaminase 1 (ADAR1 or DRADA) is an enzyme involved in the editing of mammalian messenger RNAs by the site specific conversion of adenosine to inosine. ADAR 1 is thought to play a role in the editing of transcripts encoding non-NMDA glutamate receptor subunits, the 2C subtype of serotonin receptor, as well as hepatitis delta virus antigen. |