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| Cat. No |
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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-320470 |
NB100-78452 |
200kDa Neurofilament Heavy Antibody (NF-01)//Alligatorl/Mouse |
1/EA |
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문의 |
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Subject
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200kDa Neurofilament Heavy Antibody (NF-01) |
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Description
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/ Alligatorl/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ICC, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | All | | Applications: | IHC-P, ICC, WB | | Clonality: | Monoclonal | | | Gene: | NEFH | | Purity: | Immunogen affinity purified | | Host: | Mouse | | | Specificity: | Neurofilament heavy protein (NF-01) | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Clone: | NF-01 | | Isotype: | IgG1 | | Immunogen: | Pellet of pig brain cold stable proteins after microtubule depolymerization | Gene Symbol: NEFH | Related Genes: | NEFM, NEFL, NFASC, SOD1, PRPH, GFAP, LDLR, FH, CFH, MAP2, MAPT, IGFALS, NES, REN, PRNP, AGT, MBP, UCHL1, METAP2, ACHE, HOXA9, MT1M, MAPK1, VIM, CLDN6, IL6, PSEN1, GPR158, PSEN2, RSPO4, PKP1, CDK5, ATP2A2, GAP-43, RANGAP1, MAPK9, CA3, SLC17A5, TAC1, LIF | Background: NF-H is an abundant, stable cytoplasmic protein located in neuronal cells in large axons frequently used as a cell type marker. The NF-H protein shares a high degree of structural and sequence homology with the NF-L and NF-M subunits, especially in the coiled-coil core domain. NF-M and NF-H form flexible extensions linking the neurofilament proteins to each other and other cytoplasmic proteins. Deletions and insertions in the NF-H protein have been reported in amyotrophic lateral sclerosis. The NF-01 monoclonal antibody reacts with a conserved phosphorylated epitope of NF-H present in all species and has been reported to be useful for Western blotting, immunohistochemistry using formalin-fixed, paraffin-embedded tissues and immunofluorescence staining. Species: | Reactivity: | All species, reacts with conserved phosphorylated epitope. | Applications: | Uses: | Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5 mug per 5 ml antibody dilution buffer for each mini-gel. Immunohistochemistry-paraffin. It is recommended that the reagent be titrated for optimal performance for each application. | | Dilutions: | Western Blot , Immunocytochemistry , Immunohistochemistry-Paraffin | | Concentrations: | 0.5 mg/ml | Packaging: | Buffer: | This antibody is provided in phosphate-buffered solution, pH 7.2 | | Storage: | Store at 4C. Do not freeze. | | Preservative: | Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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