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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-320483 |
NB300-133 |
160kDa Neurofilament Medium Antibody//Avian, Bovine,/Rabbit |
1/EA |
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Subject
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160kDa Neurofilament Medium Antibody |
Description
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/ Avian, Bovine,/Rabbit |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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ICC, IF, IHC-P, IHC-P, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Av, Fe, Rt, Po, Mu, Ma, Hu, Bv | Applications: | IHC-Fr, IHC-P, ICC, WB, IF | Clonality: | Polyclonal | | Gene: | NEFM | Purity: | Whole antisera | Host: | Rabbit | | Specificity: | Specifically recognizes the evolutionarily conserved extreme C-terminal region of the medium neurofilament subunit (~145-170kDa). | Publications: | Antibody has not yet been mentioned in a publication. | Details: Immunogen: | Recombinant C-terminal segment of rat NF-M | Localization: | Cytoplasmic | Gene Symbol: NEFM Entrez: | 4741 (Human) | | 18040 (Mouse) | | 24588 (Rat) | | P12839 (Rat) | Related Genes: | NEFL, NF-H, NFASC, GFAP, VIM, NEFH, PRPH, MAPT, MAP2, CDK5, SOD1, NES, MAPK1, METAP2, MAPK3, IGFALS, ENO2, MBP, NGF, EGF, MAP1B, SYP, GAP-43, MAP-2, BDNF, KIAA0101, CDK5R1, GLYAT, CAT, ENO1, PKA, EPHB2, MYB, DES, CHAT, FGF2, PRG2, FOS, NTRK1, JUN | Background: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the middle or medium neurofilament subunit and runs on SDS-PAGE gels in the range 145-170kDa, with some variation in different species. Antibodies to NF-M are useful to identify this protein and identify neurons and their processes in tissue sections and in tissue culture. NF-M can also be useful in studies of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig's disease or Alzheimer's disease. Species: Reactivity: | NB 300-133 reacts with NF-M from all mammals, birds and reptiles tested to date, including human, cat, rat, mouse, cow and pig. | Applications: Uses: | This antibody is useful for Immunofluorescence, Western Blot, Immunocytochemistry, Immunohistochemistry-Paraffin, and Immunohistochemistry-Frozen | Dilutions: | immunofluorescence 1:500-1:000, Western Blot 1:20000, Immunocytochemistry 1:5000, Immunohistochemistry-Paraffin , Immunohistochemistry-Frozen | Positive Controls: | 1 positive controls | Packaging: Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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