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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-320484 |
NB300-134 |
160kDa Neurofilament Medium Antibody (3H11)//Avian, Human,/Mouse |
1/EA |
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문의 |
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Subject
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160kDa Neurofilament Medium Antibody (3H11) |
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Description
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/ Avian, Human,/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Av, Mu, Ma, Hu | | Applications: | WB, IHC-P | | Clonality: | Monoclonal | | | Gene: | NEFM | | Purity: | Ascites | | Host: | Mouse | | | Specificity: | Specifically recognizes the medium neurofilament subunit (~145-170 kDa). | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Clone: | 3H11 | | Isotype: | IgG1 Kappa | | Immunogen: | Recombinant C-terminus of rat NF-M | | Localization: | Cytoplasmic | Gene Symbol: NEFM | Entrez: | 4741 (Human) | | | 18040 (Mouse) | | | P12839 (Rat) | | Related Genes: | NEFL, NF-H, NFASC, GFAP, VIM, NEFH, PRPH, MAPT, MAP2, CDK5, SOD1, NES, MAPK1, METAP2, MAPK3, IGFALS, ENO2, MBP, NGF, EGF, MAP1B, SYP, GAP-43, MAP-2, BDNF, KIAA0101, CDK5R1, GLYAT, CAT, ENO1, PKA, EPHB2, MYB, DES, CHAT, FGF2, PRG2, FOS, NTRK1, JUN | Background: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the middle or medium neurofilament subunit and runs on SDS-PAGE gels in the range 145-170kDa, with some variation in different species. Antibodies to NF-M are useful to identify this protein and identify neurons and their processes in tissue sections and in tissue culture. NF-M can also be useful in studies of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig's disease or Alzheimer's disease. Species: | Reactivity: | Human and mouse, as well as all other mammalian and avian species tested to date. | Applications: | Uses: | NB 300-134 can be used on cryostat sections and formalin-fixed paraffin-embedded histological sections, and Western blotting. *The investigator should determine the optimal dilution for a specific application. | | Dilutions: | Immunohistochemistry-Paraffin 1:500, Western Blot 1:2500 | | Positive Controls: | 1 positive controls | Packaging: | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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