| Swiss Prot Num | P21918 |
| Immunogen | Synthetic peptide corresponding to aa 459-477 of human D5DR |
| Product Type | Antibodies |
| Storage | Store the antibody (undiluted) at 2 – 8 °C. Shelf life: One year from despatch. |
|
| Format | State: Liquid affinity purified Ig fraction |
| ? | Buffer System: 10 mM PBS, pH 7.4 with BSA and Sodium Azide |
|
| Specificity | This antibody detects D5DR (aa 459-477). |
| Add. information | Molecular weight: 53 kDa Cellular localisation: Cell membrane and cytoplasmic |
| Application | Immunohistochemistry on paraffin sections (1:50, 30 min at RT); staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Positive control: Brain. |
| Background | The dopamine receptors are divided into two classes, D1 and D2, which differ in their functional characteristics. D1DR and D5DR compose the D1 class of dopamine receptors, and D2DR, D3DR and D4DR compose the D2 class. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. |
| Concentration | 0.2 mg/ml |
