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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-354424 |
AP07740PU-N |
DAPK2 / DRP-1//Human, Mouse, Rat/Rabbit |
1/EA |
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문의 |
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Subject
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DAPK2 / DRP-1 |
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Description
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/ Human, Mouse, Rat/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 50 ug | | Reactivity | Human, Mouse, Rat | | Presentation | Aff - Purified | | Applications | Paraffin Sections, Western blot / Immunoblot | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Not USA/Canada | | Synonyms | DAP kinase 2 | | Swiss Prot Num | Q9UIK4 | | Immunogen | Synthetic Peptide corresponding to amino acids near the carboxy terminus of human DAPK2. | | Product Type | Antibodies | |
| Immunogen | Swiss Prot Num: Q9UIK4 | | ? | Remarks: The sequence of this antigenic peptide is identical to the corresponding amino acids of mouse origin. | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. "Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity." Kawai T., Nomura F., Hoshino K., Copeland N.G., Gilbert D.J., Jenkins N.A., Akira S. Oncogene 18:3471-3480(1999). 2. "Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis." Inbal B., Shani G., Cohen O., Kissil J.L., Kimchi A. Mol. Cell. Biol. 20:1044-1054(2000). 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004). 4. "Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding." Shani G., Henis-Korenblit S., Jona G., Gileadi O., Eisenstein M., Ziv T., Admon A., Kimchi A. EMBO J. 20:1099-1113(2001). | |
| Format | State: Liquid purified IgG fraction. | | ? | Purification: Immunoaffinity Chromatography. | | ? | Buffer System: Phosphate Buffered Saline PBS containing 0.02% Sodium Azide as preservative. | |
| Specificity | Species Human, Mouse and Rat. | | Application | Immunohistochemistry on Paraffin Sections (5 ?g/ml). Western Blot (0.5-1 ?g/ml). | | Background | DAPK2, a DAPK type protein kinase, contains a N-terminal protein kinase domain followed by a conserved CaM-binding domain with significant homologies to other kinases in this subfamily. In vitro assay experiments have shown that the protein is autophosphorylated. Overexpression of the DAPK2 gene was shown to induce cell apoptosis. | |
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