| Catalog Number | GTX19926 |
| Product Name | G0 protein alpha [SPM396] antibody |
| Product Description | Mouse monoclonal [SPM396] to Go Protein alpha |
| Synonyms | 281792 | GNAO1 | |
| Background | GTP binding proteins (G proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Go belongs to the pertussis toxin sensitive G proteins. It consists of two subtypes of a subunits (ao1 and ao2) derived from alternative splicing of a single gene. ao1 differs from ao2 within the C terminal. |
| Clonality | Monoclonal |
| Clone No | SPM396 |
| Host | Mouse |
| Isotype | IgG1 |
| Immunogen | Partially purified bovine brain Go protein alpha. |
| Antigen Species | Bovine |
| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | WB: Use at a concentration of 1 - 2 μg/ml for 2hrs at RT. Predicted molecular weight: 39-42 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Species Cross Reactivity | Cross-reacts with Human, Rat, Cow and Guinea pig. Does not cross-react with Mouse. Not yet tested in other species. |
| Positive Controls | IMR5 cells Brain |
| Target | G0 protein alpha |
| Cellular Localization | Cell Membrane |
| Form Supplied | Liquid |
| Purification | Protein G purified |
| Storage Buffer | Preservative: Sodium Azide. Constituents: BSA, 10mM PBS. pH 7.4 |
| Storage Instruction | Store at 4ºC |
