| Synonyms | HADH2, HSD17B10, HADH2 protein |
| Swiss Prot Num | Q6IBS9 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ABAD. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. FASEB J. 19 (6), 597-598 (2005) 2. J. Mol. Biol. 342 (3), 943-952 (2004) 3. Science 304 (5669), 448-452 (2004) 4. FEBS Lett. 451 (3), 238-242 (1999) 5. J. Biol. Chem. 274 (21), 15014-15019 (1999) |
|
| Format | State: Liquid purified Ig |
| ? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
| ? | Buffer System: PBS with 0.09% (W/V) sodium azide |
|
| Specificity | This antibody reacts to ABAD. |
| Application | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. |
| Background | Amyloid b-peptide-binding alcohol dehydrogenase (ABAD) is a member of the family of short chain dehydrogenase/reductases; unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ABAD appears to trigger cell stress induced by the amyloid peptide. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
