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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-354811 |
H00000673-A01 |
B Raf Antibody//Human/Mouse |
1/EA |
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¹®ÀÇ |
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Subject
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B Raf Antibody |
Description
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/ Human/Mouse |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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ELISA |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Hu | Applications: | ELISA | Clonality: | Polyclonal | | Gene: | BRAF | Purity: | Whole antisera | Host: | Mouse | | Specificity: | BRAF - v-raf murine sarcoma viral oncogene homolog B1 | Details: Immunogen: | BRAF (NP_004324, 346 a.a. ~ 445 a.a) partial recombinant protein with GST tag. | Epitope: | FRPADEDHRNQFGQRDRSSSAPNVHI NTIEPVNIDDLIRDQGFRGDGGSTTG LSATPPASLPGSLTNVKALQKSPGPQ RERKSSSSSEDRNRMKTLGRRD | Gene Symbol: BRAF Entrez: | 673 (Human) | Omim: | 164757|211980 (Human) | Swiss Prot: | NP_004324 (Human) | Related Genes: | RAF1, MAPK1, ZHX2, EPHB2, KRAS, CDKN2A, HRAS, MAPK3, TP53, EGFR, NRAS, MAP2K1, MLH1, SNRPE, PIK3CG, PIK3CA, AKT1, RET, MAP2K2, PTEN, CTNNB1, MAPK12, ARAF, RAP1A, CDKN1A, MSH2, TERF2IP, APC, EGF, CCND1, ERBB2, PROC, CDK4, PIK3CB, PIK3CD, RASSF1, MGMT, TCEAL1, D4S234E, PKA | Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. Species: Reactivity: | Human. Other species not tested. | Applications: Uses: | This antibody is useful for ELISA. | Dilutions: | ELISA | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: Buffer: | This antibody is in antisera and the concentration is unavailable. | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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