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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-354818 |
H00000673-M09 |
B Raf Antibody (4F4)//Human/Mouse |
1/EA |
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문의 |
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Subject
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B Raf Antibody (4F4) |
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Description
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/ Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Monoclonal | | | Gene: | BRAF | | Purity: | IgG purified | | Host: | Mouse | | Details: | Clone: | 4F4 | | Isotype: | IgG2a Kappa | | Immunogen: | BRAF (NP_004324, 138 a.a. ~ 231 a.a) full length recombinant protein with GST tag. | Gene Symbol: BRAF | Entrez: | 673 (Human) | | Omim: | 164757, 211980, (Human) | | Swiss Prot: | NP_004324 (Human) | | Related Genes: | RAF1, MAPK1, ZHX2, EPHB2, KRAS, CDKN2A, HRAS, MAPK3, TP53, EGFR, NRAS, MAP2K1, MLH1, SNRPE, PIK3CG, PIK3CA, AKT1, RET, MAP2K2, PTEN, CTNNB1, MAPK12, ARAF, RAP1A, CDKN1A, MSH2, TERF2IP, APC, EGF, CCND1, ERBB2, PROC, CDK4, PIK3CB, PIK3CD, RASSF1, MGMT, TCEAL1, D4S234E, PKA | Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. Species: | Reactivity: | Human. Other species not tested. | Applications: | Uses: | Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA. | | Dilutions: | ELISA,Western Blot 1:500 | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Buffer: | In 1x PBS, pH 7.2 | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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