|
|
Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-354819 |
H00000673-M05 |
B Raf Antibody (4G7)//Human/Mouse |
1/EA |
|
|
|
|
¹®ÀÇ |
|
|
|
|
|
|
Subject
|
B Raf Antibody (4G7) |
Description
|
/ Human/Mouse |
Clonality
|
Mono |
Company
|
Novus biologicals |
Application
|
ELISA, Western Blot |
Conjugation
|
|
Immunogen
|
|
Contents
|
Description:Summary: Species: | Hu | Applications: | WB, ELISA | Clonality: | Monoclonal | | Gene: | BRAF | Purity: | IgG purified | Host: | Mouse | | Details: Clone: | 4G7 | Isotype: | IgG2b Kappa | Immunogen: | BRAF (NP_004324, 138 a.a. ~ 231 a.a) full length recombinant protein with GST tag. | Gene Symbol: BRAF Entrez: | 673 (Human) | Omim: | 164757, 211980, (Human) | Swiss Prot: | NP_004324 (Human) | Related Genes: | RAF1, MAPK1, ZHX2, EPHB2, KRAS, CDKN2A, HRAS, MAPK3, TP53, EGFR, NRAS, MAP2K1, MLH1, SNRPE, PIK3CG, PIK3CA, AKT1, RET, MAP2K2, PTEN, CTNNB1, MAPK12, ARAF, RAP1A, CDKN1A, MSH2, TERF2IP, APC, EGF, CCND1, ERBB2, PROC, CDK4, PIK3CB, PIK3CD, RASSF1, MGMT, TCEAL1, D4S234E, PKA | Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. Species: Reactivity: | Human. Other species not tested. | Applications: Uses: | Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. | Dilutions: | ELISA,Western Blot 1:500 | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: Buffer: | In 1x PBS, pH 7.2 | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|