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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-354941 |
H00011285-B01P |
B4GALT7 Antibody//Human/Mouse |
1/EA |
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¹®ÀÇ |
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Subject
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B4GALT7 Antibody |
Description
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/ Human/Mouse |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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ELISA, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Hu | Applications: | ELISA, WB | Clonality: | Polyclonal | | Gene: | B4GALT7 | Purity: | IgG purified | Host: | Mouse | | Specificity: | B4GALT7 - xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I), | Details: Immunogen: | B4GALT7 (NP_009186.1, 1 a.a. ~ 327 a.a) full-length human protein. | Epitope: | MFPSRRKAAQLPWEDGRSGLLSGGLP RKCSVFHLFVACLSLGFFSLLWLQLS CSGDVARAVRGQGQETSGPPRACPPE PPPEHWEEDASWGPHRLAVLVPFRER FEELLVFVPHMRRFLSRKKIRHHIYV LNQVDHFRFNRAALINVGFLESSNST DYIAMHDVDLLPLNEELDYGFPEAGP FHVASPELHPLYHYKTYVGGILLLSK QHYRLCNGMSNRFWGWGREDDEFYRR IKGAGLQLFRPSGITTGYKTF | Gene Symbol: B4GALT7 Entrez: | 11285 (Human) | Swiss Prot: | NP_009186.1 (Human) | Related Genes: | CHST11, CHSY3, HS3ST2, SULF2, EXT1, HPSE, HS2ST1, DCN, CHPF2, CSGALNACT2, CSGALNACT1 | Background: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) linkage found in proteoglycans. Manganese is required as a cofactor. This enzyme differs from the other six beta4GalTs because it lacks the conserved beta4GalT1-beta4GalT6 Cys residues and it is located in cis-Golgi instead of trans-Golgi. Two single-nucleotide mutations were identified from a patient with the progeroid type of Ehlers-Danlos syndrome. [provided by RefSeq] Species: Applications: Uses: | Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. | Dilutions: | Western Blot 1:500,ELISA | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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