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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-348019 |
NBP1-19447 |
53BP1 Antibody//Human, Mouse,/Rabbit |
1/EA |
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문의 |
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Subject
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53BP1 Antibody |
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Description
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/ Human, Mouse,/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IF, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | IF, IHC, WB | | Clonality: | Polyclonal | | | Gene: | TP53BP1 | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | 53BP1 (D2) detects endogenous levels of 53BP1 protein. | Details: Gene Symbol: TP53BP1 | Entrez: | 7158 (Human) | | Related Genes: | H2AFX, ATM, TP53, MDC1, NBN, BRCA1, ATR, MMAB, ANTXR1, MRE11A, CHEK2, NLRP2, CDKN1A, CHEK1, TERF2, ARTN, RAD9A, RAD51, CRB2, JUN, E2F1, PRKDC, RAD50, TCEAL1, NFKB1, D4S234E, RB1, RNF8, FOS, DCLRE1C, DDR1, TP53BP2, BLM, UBE2N, TBPL1, CDKN2A, HEPACAM, PAXIP1, MDM2, IFI16 | Background: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability. Species: | Reactivity: | Human, Mouse, Rat | Applications: | Uses: | This antibody is useful for Western Blot, Immunohistochemistry and Immunofluorescence. Western blot analysis of 53BP1 (D2) antibody in extracts from A549 cells. | | Dilutions: | Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200, immunofluorescence 1:50-1:200, | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Phosphate buffered saline (PBS) pH 7.2. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 15mM Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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