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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-351122 |
H00010188-D01P |
ACK1 Antibody//Human/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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ACK1 Antibody |
Description
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/ Human/Rabbit |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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ELISA, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Protein Type: | Full length Protein | Species: | Hu | Applications: | WB, ELISA | Clonality: | Polyclonal | | Gene: | TNK2 | Purity: | protein A purified | Host: | Rabbit | | Specificity: | Reacts with tyrosine kinase, non-receptor, 2. | Details: Immunogen: | TNK2 (AAH08884.1, 1 a.a. ~ 352 a.a) full-length human protein. | Epitope: | MQPEEGTGWLLELLSEVQLQQYFLRL RDDLNVTRLSHFEYVKNEDLEKIGMG RPGQRRLWEAVKRRKALCKRKSWMSK VFSGKRLEAEFPPHHSQSTFRKTSPA PGGPAGEGPLQSLTCLIGEKDLRLLE KLGDGSFVVVRRGEWDAPSGKTVSVA VKCLKPDVLSQPEAMDDFIREVNAMH SLDHRNLIRLYGVVLTPPMKMVTELA PLGSLLDRLRKHQGHFLLGTLSRYAV QVAEGMGYLESKRFIHRDLAA | Gene Symbol: TNK2 Entrez: | 10188 (Human) | Swiss Prot: | AAH08884.1 (Human) | Related Genes: | CDC42, EGFR, EGF, AKT1, WAS, ERRFI1, SRC, RHO, RASGRF1, RHOD, ACSS2, PTCRA, BCAR1, NCK1, SNX9, ABL1, SOS2, SOS1, MAPK1, GRB2, ACCS, MTTP, PLA2G15, IL2, RHOQ, MAPK8, SHC1, WWOX, CBL, HSH2D, PTK2B, FES, TNK1, JUN, MAPK9, GLYAT, TF, TFAP2A, GSTP1, HCK | Background: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq] Species: Applications: Uses: | This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA. | Dilutions: | ELISA,Western Blot | Notes: Genbank Accession: BC008884.2 This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: Buffer: | 1x PBS, pH 7.2 | Storage: | Store at -20C. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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